Changzhou Niujin Shisong Biotechnology Company Ltd.

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Recombinant Overlapping Mycobacterium tuberculosis peptides of ESAT6-CFP10
Details

Product Introduction

Number of Amino acids

304

Molecular Weight

33kDa

Purity(SDS-PAGE)

≥90%

Endotoxin

10EU/mg

Storage condition

-20℃

Packing

Tube

 

Functional Properties

Mycobacterium tuberculosis ESAT6-CFP10 Protein (ROP-TB) is  a modification of ESAT6 and CFP10, which can be used as an effective lymphocyte antigen, and the stimulation effect is better than ESAT6 and CFP10 fusion recombinant protein.

We has developed a new technique, Recombinant Overlapping peptides, to stimulate and monitor the immune response of CD8+ and CD4+ T cells.

 

Related Papers

1, Comparing Pooled Peptides with Intact Protein for Accessing Cross-presentation Pathways for Protective CD8+ and CD4+ T Cells. The Journal of Biological Chemistry 284: 9184-9191, 2009.

2, Immunization with different formulations of Mycobacterium tubrculosis antigen 85A induces immune responses with different specificity and protective efficacy,Vaccine 31:4624– 46312013.

3, Cai L, Zhang J, Zhu R, et al. Protective cellular immunity generated by cross-presenting recombinant overlapping peptide proteins[J]. Oncotarget, 2017, 8(44):76516-76524.